ATAC-Seq; axon regeneration; chromatin accessibility; spinal cord injury; transcription factors;Mendeley Import (Apr 03)

Developmental chromatin restriction of pro-growth gene networks acts as an epigenetic barrier to axon regeneration in cortical neurons

Axon regeneration in the central nervous system is prevented in part by a developmental decline in the intrinsic regenerative ability of maturing neurons. This loss of axon growth ability likely reflects widespread changes in gene expression, but the …